The purpose of this paper is to present study of thermal creep stress and strain rates in a non-homogeneous spherical shell by using Seth’s transition theory. Seth’s transition theory is applied to the problem of creep stresses and strain rates in the non-homogeneous spherical shell under steady-state temperature. Neither the yield criterion nor the associated flow rule is assumed here. With the introduction of thermal effect, values of circumferential stress decrease at the external surface as well as internal surface of the spherical shell. It means that the temperature dependent materials minimize the possibility of fracture at the internal surface of the spherical shell. The model proposed in this paper is used commonly as a design of chemical and oil plants, industrial gases and stream turbines, high speed structures involving aerodynamic heating.