Noether’s theorem is applied into a multi-scale mechno-electrophysiological coupling model
of neuron membrane dynamics. The Euler-Lagrange equations in generalized coordinates of
this model are deduced by the nonconservative Hamilton principle. The Noether symmetry
criterion and conserved quantities based on the Lie point transformation group are given. The
influence of external non-potential forces and material parameters on the forms of Noether
conserved quantities is detailed discussed, which indicates that the conserved quantities are
very depending on the loading rate and mechanical parameters of the membrane.
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